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AetnaAll Plans · Coverage · Medical Policy · OphthalmologyLow impact

Anecortave Acetate (Retaane) (CPB 0706, reviewed 2025-11-24)

Effective date
Not stated in the notice
Identified
Aug 17, 2026

Summary

Historical Aetna clinical policy bulletin (CPB 0706, reviewed 2025-11-24, first detected by PolicyChanges 2026-08-17) that states Aetna considers anecortave acetate (Retaane) experimental, investigational or unproven for age-related macular degeneration, glaucoma and retinoblastoma because its effectiveness has not been established. No effective date is stated, so check current applicability before acting. Billing teams that bill these diagnoses should confirm the drug is not on their charge lists and route any claims for it to the provider for review.

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What to do

Action · 3 steps
01No effective date is stated in the source, and this is older material newly discovered, so check current applicability on the Aetna site before acting.
02Billing team: search charge entry and the drug list for anecortave acetate (Retaane) and, if it appears on any claim for the listed ICD-10 diagnoses (retinoblastoma C69.20 to C69.22, age-related macular degeneration H35.3110 to H35.3293, glaucoma H40.001 to H42), send the claim to the provider for review before submission.
03Providers: confirm the drug is documented as experimental for these indications before it is ordered for an Aetna patient.

Codes mentioned

C69.20C69.22H35.3110H35.3293H40.001H42

Original notice

Anecortave Acetate (Retaane) (CPB 0706, reviewed 2025-11-24)
aetna.com · Always check the source before changing claims.
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