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Brachytherapy (CPB 0371, reviewed 2026-05-20)

Aetna·Oncology, Radiation Oncology, Urology +5 more·Medical Policy
Effective date
May 20, 2026
We identified it
Aug 19, 2026
Days to comply

Summary

Aetna updated its Brachytherapy clinical policy (CPB 0371) effective May 20, 2026, clarifying covered procedures, radioelement sources, and placement codes while explicitly designating electronic brachytherapy (AccuBoost, Xoft Axxent eBx) and endovascular brachytherapy for re-stenosis as experimental/investigational and not covered. Billing teams must verify medical necessity against EviCore guidelines and ensure claims use only covered CPT/HCPCS codes for approved indications.

Action Required

Action needed
By May 20, 2026: (1) Billing team must update claim submission rules in billing software to DENY any claims for CPT codes 0394T and 0395T (electronic brachytherapy) and endovascular brachytherapy (CPT 37224 for re-stenosis indications) — these are now explicitly non-covered as experimental/investigational. (2) Prior to claim submission, verify all brachytherapy claims against EviCore Healthcare Radiation Therapy Clinical Guidelines for medical necessity. (3) For breast brachytherapy claims using CPT 19296, 19297, 19298, ensure proper documentation of placement timing relative to partial mastectomy. (4) For prostate brachytherapy (CPT 55875, 55876), confirm medical necessity per EviCore guidelines and document that brachytherapy is not being billed as ProstRcision (combination approach not proven superior). (5) Update claim scrubbing logic to flag any submission of C2616, C2643 (yttrium-90, cesium-131 sources) or other radioelement sources (C1716-C1717, C2634-C2642, C2698-C2699) without corresponding approved placement CPT codes. (6) Provider education team must communicate to all ordering physicians that electronic brachytherapy systems (AccuBoost, Xoft Axxent eBx) are NOT covered for any indication including breast cancer and dermatologic uses. Failure to implement these controls will result in claim denials and potential compliance violations.

Affected Billing Codes

19296
19297
19298
20555
41019
49327
49412
55875
55876
55920
57156
61770
77316
77317
77318
77750
77761
77762
77763
77767
77768
77770
77771
77772
77778
77789
77799
37224
A9527
C1715
C1716
C1717
C1719
C2616
C2634
C2635
C2636
C2637
C2638
C2639
C2640
C2641
C2642
C2643
C2645
C2698
C2699
C9725
C9726
C9728
Q3001
A4648
A4650
C1739