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Genotyping for 9p21 Single Nucleotide Polymorphisms to Predict Risk of Cardiovascular Disease or Aneurysm
Blue Cross & Blue Shield of Mississippi·MS · Cardiology, Internal Medicine, Family Medicine +1 more·Medical Policy
We identified it
Jun 20, 2026
Summary
This policy confirms that genotyping for 9p21 single nucleotide polymorphisms to predict cardiovascular disease or aneurysm risk remains investigational and non-covered. The policy was reviewed on 07/31/2025 with no changes to the investigational status.
Action Required
No immediate action required. Continue to deny coverage for 9p21 SNP genotyping tests (CPT 81479, 84999) as investigational. Inform providers that these genetic tests for cardiovascular risk prediction are not covered and patients would be responsible for full payment if ordered.