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Blue Cross & Blue Shield of MississippiAll Plans · Billing Codes · Medical Policy · Genetics, Pathology, Gastroenterology +1 moreMedium impact

Miscellaneous Genetic and Molecular Diagnostic Tests

Effective date
Jul 1, 2025
Identified
Jun 20, 2026

Summary

All tests listed in this policy are considered investigational. The policy covers miscellaneous genetic and molecular diagnostic tests not addressed in a separate review, and conclusions from a separate policy supersede this one. The code reference adds CPT 0548U (GFAP chemiluminescent immunoassay using plasma) effective 2025-04-01 and CPT 0570U (GFAP and UCH-L1 immunoassay for traumatic brain injury) effective 2025-07-01.

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What to do

Action · 3 steps
01Already effective 2025-04-01 and 2025-07-01: Billing team: Check the investigational codes table in charge entry before billing any test under this policy, including CPT 0548U and 0570U, since all tests listed in this policy are considered investigational.
02Billing team: Treat genetic testing as investigational when BCBSMS criteria are not met, including when there is insufficient evidence to determine that the technology results in an improvement in the net health outcome.
03check current applicability at the source link before billing.

Codes mentioned

813828147982397827848352084999860218614086255870458704687075871028717787209873288732987336877988834688350

Original notice

Miscellaneous Genetic and Molecular Diagnostic Tests
bcbsms.com · Always check the source before changing claims.
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Related policy hubs

Blue Cross & Blue Shield of Mississippi policiesGeneticsPathologyGastroenterologyNeurologyCode 81382Code 81479Code 82397Code 82784Code 83520Code 84999Code 86021Code 86140Code 86255Code 87045Code 87046Code 87075Code 87102Code 87177Code 87209Code 87328Code 87329Code 87336Code 87798Code 88346Code 88350

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