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Blue Cross & Blue Shield of MississippiAll Plans · Coverage · Medical Policy · Genetics, OncologyMedium impact

Use of Common Genetic Variants (Single Nucleotide Variants) to Predict Risk of Nonfamilial Breast Cancer

Effective date
Not stated in the notice
Identified
Jun 20, 2026

Summary

BCBSMS considers testing for one or more single nucleotide variants (SNVs) to predict an individual's risk of breast cancer investigational. The policy states that the GeneType breast cancer risk test is investigational for all indications, including use as a method of estimating individual risk for developing breast cancer. The policy was reviewed on 04/21/2026 with no changes.

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What to do

Action · 3 steps
01Billing team: Under this policy, SNV testing to predict breast cancer risk is investigational.
02The policy's Policy Guidelines define investigative services as not yet recognized as a generally accepted standard of good medical practice and therefore not considered medically necessary.
03Codes 81479 (unlisted molecular pathology procedure) and 81599 (unlisted multianalyte assay with algorithmic analysis) are listed in the Investigational Codes table of this policy.

Codes mentioned

8147981599

Original notice

Use of Common Genetic Variants (Single Nucleotide Variants) to Predict Risk of Nonfamilial Breast Cancer
bcbsms.com · Always check the source before changing claims.
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