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Use of Common Genetic Variants (Single Nucleotide Variants) to Predict Risk of Nonfamilial Breast Cancer
Blue Cross & Blue Shield of Mississippi·MS · Oncology, OB-GYN, Family Medicine +1 more·Medical Policy
Effective date
Jan 8, 2025
We identified it
Jun 20, 2026
Summary
BCBS MS updated their policy on genetic testing for breast cancer risk prediction, maintaining that all single nucleotide variant (SNV) testing and GeneType breast cancer risk tests remain investigational and not covered. No changes to coverage status - these tests continue to be considered investigational.
Action Required
Immediately: Billing team should verify that CPT codes 81479 and 81599 for genetic variant testing related to breast cancer risk prediction are flagged as non-covered/investigational in billing system. Continue to inform patients these tests are not covered by BCBS MS and require self-pay or alternative coverage verification.