Rebreathing of Inert Gas for Measurement of Cardiac Output and Validation of Intra-Cardiac Shunt (CPB 0714, reviewed 2026-10-20)
Aetna clinical policy bulletin 0714, last reviewed October 20, 2026, covers rebreathing of inert gas for measuring cardiac output and for validating intra-cardiac shunt. The policy considers three uses experimental, investigational or unproven because their effectiveness has not been established: measuring cardiac output, predicting survival in persons with pulmonary hypertension, and validating intra-cardiac shunt.