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AetnaAll Plans · Coverage · Medical Policy · Cardiology, PulmonologyMedium impact

Rebreathing of Inert Gas for Measurement of Cardiac Output and Validation of Intra-Cardiac Shunt (CPB 0714, reviewed 2025-11-25)

Effective date
Not stated in the notice
Identified
Aug 15, 2026

Summary

Rebreathing of inert gas for the measurement of cardiac output, for the prediction of survival in persons with pulmonary hypertension, and for the validation of intra-cardiac shunt is considered experimental, investigational, or unproven because the effectiveness of these approaches has not been established. The policy lists ICD-10 codes I27.0, I27.20 to I27.29 (pulmonary hypertension) and Q21.0 to Q21.9 (congenital malformations of cardiac septa, intra cardiac shunt) as not covered for the indications listed in the policy. The policy lists no specific CPT or HCPCS codes for measuring cardiac output with inert gas rebreathing.

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What to do

Action · 3 steps
01Billing team: Before billing inert gas rebreathing services, check that the indication is not one the policy lists as experimental, investigational, or unproven: measurement of cardiac output, prediction of survival in persons with pulmonary hypertension, or validation of intra-cardiac shunt.
02Claims with ICD-10 codes I27.0, I27.20 to I27.29, or Q21.0 to Q21.9 are listed as not covered for the indications in the policy.
03The policy lists no specific CPT or HCPCS codes for measurement of cardiac output.

Codes mentioned

I27.0I27.20I27.29Q21.0Q21.9

Original notice

Rebreathing of Inert Gas for Measurement of Cardiac Output and Validation of Intra-Cardiac Shunt (CPB 0714, reviewed 2025-11-25)
aetna.com · Always check the source before changing claims.
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