Identification of Microorganisms Using Nucleic Acid Probes
Effective October 1, 2026, nucleic acid probe testing with or without quantification may be considered medically necessary for BK virus, cytomegalovirus, hepatitis B, hepatitis C, hepatitis D, HIV-1, HIV-2, human herpesvirus 6 and influenza virus. Respiratory pathogen panels with 12 or more targets are considered not medically necessary. Quantification for other microorganisms, hepatitis G testing, central nervous system pathogen panels, urinary tract infection panels, joint infection panels, endometrial pathogen panels, pathogen panels for surgical or chronic wounds and oral HPV testing are considered investigational.