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Independence Blue CrossMedicare Advantage · Billing Codes · Medical Policy · Allergy & Immunology, Hematology, Oncology +6 moreMedium impact

MA08.009w, Immune Globulin Intravenous (IVIG), Subcutaneous (SCIG)

Effective date
Jan 1, 2025
Identified
Jun 19, 2026

Summary

Independence Blue Cross updated MA08.009w to MA08.009z effective 01/01/2025, replacing HCPCS code J1599 (generic immune globulin) with J1552 (Alyglo, a specific branded formulation) for IVIG billing. This change clarifies coding specificity for a particular immune globulin product and requires billing system updates to reflect the new code.

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What to do

Action · 5 steps
01By 01/01/2025: Billing team must update the billing system to replace HCPCS code J1599 with J1552 for Alyglo immune globulin intravenous claims under Independence Blue Cross Medicare Advantage plans.
02Remove J1599 from all fee schedules, encounter forms, and claim submission templates.
03Update the superbill and any internal coding references to reflect J1552 as the correct code for Alyglo.
04Communicate the change to all providers who administer IVIG to ensure they document the specific product (Alyglo) on orders.
05Claims submitted with J1599 for Alyglo after 01/01/2025 may be denied or require rework.

Codes mentioned

J1552J1599J1555J1558J1559J1561J1569J1575

Original notice

MA08.009w, Immune Globulin Intravenous (IVIG), Subcutaneous (SCIG)
medpolicy.ibx.com · Always check the source before changing claims.
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Related changes

See all Independence Blue Cross changes →
MA08.009y, Immune Globulin Intravenous (IVIG), Subcutaneous (SCIG)MediumEffective Apr 1, 2026 · Medical Policy08.00.13am, Immune Globulin Intravenous (IVIG), Subcutaneous (SCIG)HighEffective Jan 1, 2026 · Medical PolicyMA08.009z, Immune Globulin Intravenous (IVIG), Subcutaneous (SCIG)LowEffective Jul 1, 2026 · Medical Policy08.00.13ao, Immune Globulin Intravenous (IVIG), Subcutaneous (SCIG)LowEffective Jul 1, 2026 · Medical PolicyBrowse every Independence Blue Cross change in the policy list

Related policy hubs

Independence Blue Cross policiesAllergy & ImmunologyHematologyOncologyNeurologyRheumatologyDermatologyInfectious DiseaseTransplant SurgeryPediatricsCode J1552Code J1599Code J1555Code J1558Code J1559Code J1561Code J1569Code J1575

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