CommercialPrior AuthMedium impact
08.01.80d, Intravenous Ketamine (Ketalar®) and Intranasal Esketamine (Spravato®)
Independence Blue Cross·Psychiatry, Pain Management·Pharmacy
Effective date
Dec 29, 2025
We identified it
Jun 19, 2026
Summary
Policy 08.01.80d establishes new medical necessity criteria for intravenous ketamine (Ketalar®) and intranasal esketamine (Spravato®). This recent policy change (effective 12/29/2025) updates coverage requirements and likely impacts prior authorization and documentation standards for these specialty psychiatric medications.
Action Required
By 12/29/2025: Billing and clinical teams must review the full policy text at the provided URL to identify specific medical necessity criteria, prior authorization requirements, and documentation standards for ketamine/esketamine claims. Update billing system rules, prior auth workflows, and provider encounter documentation templates accordingly. Ensure all claims submitted after the effective date include required medical necessity documentation. Contact the payer (IBX) for specific billing codes and authorization procedures if not detailed in the full policy. Claims submitted without meeting the new medical necessity criteria may be denied.