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UnitedHealthcareMedicare Advantage · Billing Codes · Medical Policy · Pathology, Oncology, Internal Medicine +1 moreHigh impact

Clinical Diagnostic Laboratory Services

Effective date
Nov 1, 2026
Identified
Nov 7, 2026

Summary

UnitedHealthcare's Medicare Advantage November 2026 update to Clinical Diagnostic Laboratory Services adds 0631U through 0659U to the CPT/HCPCS codes that are not covered when submitted with a screening diagnosis, and removes 0167U, 0204U, 0206U, 0207U, 0289U, 0393U, 0396U, 0412U, 0443U, 0479U, 0503U, 0547U, 0568U, 0596U, 0616U, and 83884 from that list. It also adds a coding clarification that ICD-10 codes Z82.49 and Z83.2 are excluded from non-coverage for CPT 81240 and 81241, removes Z59.7 from the non-covered diagnosis codes, and notes that 0556U, 0557U, and 0585U were deleted Sep. 30, 2026. Billing teams should update claim edits and screening-diagnosis workflows for these codes.

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What to do

Action · 6 steps
01Effective 2026-11-01: Billing team should update claim edits and charge entry so that CPT codes 0631U through 0659U are not submitted with a screening diagnosis, and remove the edits for 0167U, 0204U, 0206U, 0207U, 0289U, 0393U, 0396U, 0412U, 0443U, 0479U, 0503U, 0547U, 0568U, 0596U, 0616U, and 83884 from that screening-diagnosis rule.
02Verify that ICD-10 Z82.49 and Z83.2 are handled as excluded from non-coverage for CPT 81240 and 81241, and that Z59.7 is no longer treated as a non-covered diagnosis.
03For 0648U, review NCD 90.2 Next Generation Sequencing documentation before billing.
04Stop submitting 0556U, 0557U, and 0585U, which the source notes were deleted Sep.
0530, 2026, and inform providers and front desk staff of these charge-entry changes.
06Claims submitted with a screening diagnosis for the listed codes will be denied under the payer's non-coverage rule.

Codes mentioned

838848124081241Z82.49Z83.2Z59.7

Original notice

Clinical Diagnostic Laboratory Services
uhcprovider.com · Always check the source before changing claims.
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