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SC Medicaid - SCDHHSMedicaid · Prior Auth · Prior Authorization · SCMedium impact

Updated Prior Authorization Expansion on Physician-Administered Drugs

Effective date
Nov 15, 2025
Identified
Jun 18, 2026

Summary

South Carolina Medicaid is expanding prior authorization requirements for additional physician-administered drugs for fee-for-service Medicaid members effective November 15, 2025. Prior authorization requests must be submitted to Prime Therapeutics Management through their online portal or phone system.

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What to do

Action · 4 steps
01Before November 15, 2025: Billing team must review the updated list of physician-administered drugs requiring prior authorization in the SCDHHS Physicians Services Provider Manual.
02Update billing system to flag these medications for prior auth verification before administration to South Carolina fee-for-service Medicaid patients.
03Train staff to submit PA requests through gatewaypa.com or call 1-800-424-8219.
04Claims will be denied without proper prior authorization.

Original notice

Updated Prior Authorization Expansion on Physician-Administered Drugs
scdhhs.gov · Always check the source before changing claims.
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