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AetnaAll Plans · Coverage · Medical Policy · Endocrinology, Internal Medicine, Nephrology +1 moreMedium impact

Vitamin D Assay (CPB 0945, reviewed 2025-12-23)

Effective date
Not stated in the notice
Identified
Aug 12, 2026

Summary

Aetna considers measurements of serum 25-hydroxyvitamin D experimental, investigational, or unproven for routine preventive screening. CPT codes 0038U, 82306 and 82652 are covered if selection criteria are met, and ICD-10 codes covered if selection criteria are met include vitamin D deficiency (E55.0 to E55.9), chronic kidney disease (N18.1 to N18.9) and osteoporosis (M80.00xA to M81.8). ICD-10 codes not covered for the indications listed in the policy include malignant neoplasms of the breast (C50.011 to C50.929) and prostate (C61), diabetes mellitus (E08.00 to E13.9), Alzheimer's disease (G30.0 to G30.9) and screening encounters for malignant neoplasms (Z12.0 to Z12.9).

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What to do

Action · 3 steps
01Billing team: Claims for CPT 0038U, 82306 and 82652 need documentation that the selection criteria in the policy are met, because these codes are covered only when those criteria are met.
02Billing team: Serum 25-hydroxyvitamin D measurement for routine preventive screening is considered experimental, investigational or unproven, so do not bill it as a covered service for that purpose.
03Billing team: For the ICD-10 codes listed as not covered for the indications in the policy, do not bill those indications as covered.

Codes mentioned

8230682652A28.1A32.9B20B59E63.9E64.3E66.01E66.9E67.3E83.31E83.32Z98.84Z21Z79.899

Original notice

Vitamin D Assay (CPB 0945, reviewed 2025-12-23)
aetna.com · Always check the source before changing claims.
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