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HumanaMedicaid · Prior Auth · Medicaid · IN · Oncology, Hematology, PediatricsMedium impact

Oncaspar® (pegaspargase) (Revised)

Act
by Jul 22, 2026
Effective date
Jul 22, 2026
Identified
Jul 21, 2026

Summary

Humana Indiana Medicaid revised its Oncaspar (pegaspargase) coverage policy, effective July 22, 2026. This is a prior authorization requirement for pegaspargase used in multi-agent chemotherapy regimens for acute lymphoblastic leukemia (ALL). The policy includes specific approval criteria, exclusions based on prior adverse events, and a 6-month initial and renewal authorization period.

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What to do

by Jul 22, 2026 · 6 steps
01Billing team must implement prior authorization requirement for Oncaspar (pegaspargase) claims for Indiana Medicaid members.
02Update billing software to flag all J9262 claims for prior auth before submission.
03Providers must verify patient meets ALL criteria (ALL diagnosis + use in multi-agent chemotherapy regimen) and does NOT have ANY exclusions (prior disease progression on asparaginase, thrombosis history, pancreatitis history, hemorrhagic events history, or bilirubin >10x ULN) before requesting authorization.
04Set up authorization tracking for 6-month initial and 6-month renewal periods.
05Claims submitted without prior authorization will be denied.
06Front-desk staff should alert oncology providers of this requirement during routine scheduling.

Codes mentioned

J9262

Original notice

Oncaspar® (pegaspargase) (Revised)
mcp.humana.com · Always check the source before changing claims.
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