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Independence Blue CrossMedicare Advantage · Administrative · Medical Policy · NJ · Transplant Surgery, Infectious Disease, Internal Medicine +1 moreLow impact

MA06.018a, Immune Cell Function Assay

Effective date
Not stated in the notice
Identified
Jun 25, 2026

Summary

This is a reissue with no substantive changes to Independence Blue Cross Medicare Advantage policy MA06.018a. The policy continues to classify immune cell function assay (ImmuKnow) as experimental/investigational and non-covered for all indications, including transplant monitoring. Despite FDA clearance, the company maintains its position that safety and effectiveness cannot be established through peer-reviewed literature review.

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What to do

Action · 4 steps
01No action required.
02This is a routine annual reissue with no changes to coverage policy.
03Continue current billing practices: deny all claims for CPT 86352 (immune cell function assay) submitted under Independence Blue Cross Medicare Advantage plans.
04Maintain existing edits in billing system that flag this code as non-covered/experimental.

Codes mentioned

86352

Original notice

MA06.018a, Immune Cell Function Assay
medpolicy.ibx.com · Always check the source before changing claims.
View original ↗

Related changes

See all Independence Blue Cross changes →
06.02.37a, Immune Cell Function AssayLowNo effective date · Medical PolicyMA06.018a, Immune Cell Function AssayLowNo effective date · Medical Policy06.02.37a, Immune Cell Function AssayLowNo effective date · Medical PolicyBrowse every Independence Blue Cross change in the policy list

Related policy hubs

Independence Blue Cross policiesNJ policy changesTransplant SurgeryInfectious DiseaseInternal MedicinePathologyCode 86352

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