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Anti-CCP Testing for Rheumatoid Arthritis
Blue Cross & Blue Shield of Mississippi·MS · Rheumatology, Internal Medicine, Family Medicine·Medical Policy
We identified it
Jun 20, 2026
Summary
This policy establishes coverage criteria for anti-CCP testing in rheumatoid arthritis diagnosis, allowing up to 2 tests per calendar year for diagnostic workup but considering it investigational for monitoring disease activity or treatment response.
Action Required
Immediately: Billing team must verify anti-CCP testing (CPT 86200) is only billed for diagnostic purposes with appropriate rheumatoid arthritis-related ICD-10 codes, limiting to maximum 2 tests per calendar year per patient. Do not bill for disease monitoring or treatment response purposes as these will be denied as investigational.