All PlansCoverageLow impact
Antigen Leukocyte Antibody Test (ALCAT)
Blue Cross & Blue Shield of Mississippi·MS · Allergy & Immunology, Gastroenterology, Family Medicine +1 more·Medical Policy
Effective date
Jan 28, 2025
We identified it
Jun 20, 2026
Summary
The Antigen Leukocyte Antibody Test (ALCAT) policy has been updated to clarify that this test is considered investigational for all indications and is not covered. The policy now includes updated information about ALCAT test panels and maintains that the test is not medically necessary.
Action Required
Immediately: Billing team should verify that CPT code 83516 for ALCAT testing is flagged as investigational/non-covered in billing system. Claims for ALCAT testing will be denied. Inform providers that this test is not covered and patients should be notified of financial responsibility before testing.