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Blue Cross & Blue Shield of MississippiCommercial · Coverage · Medical Policy · MS · NeurologyLow impact

State and School Employees' Health Insurance Plan - Qalsody (tofersen)

Act
immediately
Effective date
Not stated in the notice
Identified
Jun 20, 2026

Summary

The Mississippi State and School Employees' Health Insurance Plan has classified Qalsody (tofersen) as investigational for ALS treatment, meaning it will not be covered due to insufficient evidence of clinical benefit. Claims for this medication and its administration will be denied.

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What to do

immediately · 3 steps
01Billing team must flag HCPCS code J1304 (tofersen injection) as non-covered investigational treatment in billing system.
02Inform providers that Qalsody claims for Mississippi State and School Employees plan members will be denied.
03Update encounter forms to note investigational status.

Codes mentioned

J1304

Original notice

State and School Employees' Health Insurance Plan - Qalsody (tofersen)
bcbsms.com · Always check the source before changing claims.
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