PolicyChanges tracks payer policy changes for medical practices and tells you what to do before they take effect.

Create a free accountPolicy Monitoring is free. No card required.
← Back to list
Blue Cross & Blue Shield of MississippiCommercial · Coverage · Medical Policy · MS · PsychiatryMedium impact

State and School Employees' Health Insurance Plan - Erzofri (paliperidone palmitate)

Act
by Aug 1, 2025
Effective date
Aug 1, 2025
Identified
Jun 20, 2026

Summary

Blue Cross Blue Shield of Mississippi has established a new policy stating that Erzofri (paliperidone palmitate) injections are considered not medically necessary for treating schizophrenia and schizoaffective disorder due to available alternatives. All services related to delivery and administration require prior authorization approval through BCBSMS.

Get alerts when payers change rules like this one

We check Blue Cross & Blue Shield of Mississippi and other payers every day and email you when a change matches your specialty and state.

Get Blue Cross & Blue Shield of Mississippi alertsPolicy Monitoring is free. No card required.

What to do

by Aug 1, 2025 · 3 steps
01Billing team must update system to flag HCPCS code J2428 (Erzofri injections) as requiring prior authorization through BCBSMS PA review process before administration.
02Update encounter forms and EMR to alert providers that this medication is considered not medically necessary by BCBSMS and alternative covered medications should be considered first.
03Claims without prior authorization will be denied.

Codes mentioned

J2428

Original notice

State and School Employees' Health Insurance Plan - Erzofri (paliperidone palmitate)
bcbsms.com · Always check the source before changing claims.
View original ↗

Related policy hubs

Summaries are AI-assisted. Always confirm against the original payer notice.

What is PolicyChanges

One workspace for payer rules, prior auth, coding and compliance

Medical practices use PolicyChanges to catch payer changes before they cause denials. Every change is summarized in plain English, with the codes involved, the date it takes effect and what to do.

Start freePolicy Monitoring is free. No card required.
Get alerts for changes like thisPolicy Monitoring is free. No card required.Create a free account