CommercialCoverageLow impact
Confocal Laser Endomicroscopy
Blue Cross & Blue Shield of Mississippi·MS · Gastroenterology·Medical Policy
We identified it
Jun 20, 2026
Summary
BCBS Mississippi has updated their medical policy for Confocal Laser Endomicroscopy (CLE), maintaining that this advanced endoscopic imaging technology is considered investigational and not covered. The policy affects gastroenterology procedures where CLE might be used as an alternative to traditional biopsy during colonoscopy or for Barrett's esophagus surveillance.
Action Required
Immediately: Billing team should ensure that Confocal Laser Endomicroscopy procedures are not billed to BCBS Mississippi as they are considered investigational and will be denied. Gastroenterology providers should be informed that CLE procedures are not covered and patients should be advised of potential out-of-pocket costs if this technology is used.