CommercialBilling CodesMedium impact
Multitarget Polymerase Chain Reaction Testing for Diagnosis of Bacterial Vaginosis
Blue Cross & Blue Shield of Mississippi·OB-GYN, Family Medicine, Internal Medicine·Medical Policy
Effective date
Jan 1, 2025
We identified it
Jun 20, 2026
Summary
Blue Cross Blue Shield policy A.2.04.127 confirms that multitarget polymerase chain reaction (PCR) testing for bacterial vaginosis diagnosis remains investigational and not covered. The policy added new CPT code 81515 effective January 1, 2025, and will add code 0557U effective July 1, 2025.
Action Required
By January 1, 2025: Billing team must ensure CPT code 81515 is flagged as investigational/non-covered in billing system for BCBS claims. By July 1, 2025: Add CPT code 0557U to investigational codes list. Verify all multitarget PCR BV testing codes (0330U, 0402U, 0505U, 81513, 81514, 81515, 0557U) are marked as non-covered to prevent claim denials.