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Blue Cross & Blue Shield of MississippiCommercial · Billing Codes · Medical Policy · Infectious Disease, OB-GYN, PathologyMedium impact

Multitarget Polymerase Chain Reaction Testing for Diagnosis of Bacterial Vaginosis

Effective date
Sep 30, 2026
Identified
Jun 20, 2026

Summary

Multitarget polymerase chain reaction (PCR) testing for the diagnosis of bacterial vaginosis is investigational under this BCBSMS policy. Investigative technology is defined as not considered medically necessary. Already effective 09/30/2026, CPT code 0557U is marked as deleted in the code reference.

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What to do

Action · 4 steps
01Billing team: Do not bill multitarget PCR testing for the diagnosis of bacterial vaginosis as medically necessary, because this policy considers it investigational.
02Under the policy's definition, investigational services are not considered medically necessary.
03Already effective 09/30/2026: Check that CPT 0557U is not used on new claims, since the investigational codes list marks it as deleted as of 09/30/2026.
04Listed investigational codes include CPT 0330U, 0402U, 0505U and 0557U, and CPT 81513, 81514, 81515 and 87999 appear in the same code reference.

Codes mentioned

81513815148151587999

Original notice

Multitarget Polymerase Chain Reaction Testing for Diagnosis of Bacterial Vaginosis
bcbsms.com · Always check the source before changing claims.
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