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Excellus BlueCross BlueShieldAll Plans · Coverage · Transplants · Transplant Surgery, Endocrinology, NephrologyMedium impact

Pancreas Transplant: (Pancreas Transplant Alone, Pancreas Transplant after Kidney Transplant, Simultaneous Pancreas Kidney Transplant): Islet Cell Transplant 7.02.01

Effective date
Mar 19, 2026
Identified
Jun 20, 2026

Summary

Excellus BlueCross BlueShield policy 07.02.01 covers pancreas transplant alone for insulin-dependent diabetes that is difficult to manage, when the patient has had frequent, acute, and severe metabolic complications requiring medical attention, consistent failure of insulin-based management, and no advanced kidney disease (stage IV or V). Pancreas transplant after kidney transplant and simultaneous pancreas-kidney transplant are considered medically appropriate under listed criteria. A second pancreas transplant after a failed primary transplant is considered medically appropriate for individuals who still meet transplant criteria. Autologous islet cell transplantation is considered medically appropriate as an adjunct to total or near-total pancreatectomy in chronic pancreatitis. Allogeneic islet cell transplantation with FDA-approved donislecel-jujn (Lantidra) is considered investigational for type 1 diabetes. This version is effective March 19, 2026.

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What to do

Action · 5 steps
01Already effective March 19, 2026: Transplant re-authorization must be completed annually while the patient is actively waiting for a transplant.
02Re-authorization documentation must be within the past 11 months unless specified, and should include an updated list of diagnoses, current functional ability (Karnofsky, PPS, ECOG or Lansky score), follow-up oral health evaluation, and the lab, cardiac and pulmonary assessments that apply.
03Pre-transplant evaluation documentation must include confirmation of diagnosis, comorbidities, performance status, oral health evaluation, lab tests, cardiac and pulmonary assessment, and age-appropriate screening.
04Prior authorization is contract dependent, and approval for all transplants, including arrangements with an approved transplant center, may be required.
05CPT 0584T, 0585T and 0586T and HCPCS G0341, G0342, G0343 and S2102 are E/I when used for Lantidra, so billing team should check that use before billing these codes.

Codes mentioned

4816048552485544855650340503605036550370G0341G0342G0343S2102S2065M32.14M32.15M35.04N08N16

Original notice

Pancreas Transplant: (Pancreas Transplant Alone, Pancreas Transplant after Kidney Transplant, Simultaneous Pancreas Kidney Transplant): Islet Cell Transplant 7.02.01
excellusbcbs.com · Always check the source before changing claims.
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