Start free

PolicyChanges tracks payer policy changes for medical practices and tells you what to do before they take effect.

Create a free accountPolicy Monitoring is free. No card required.
← Back to list
Excellus BlueCross BlueShieldAll Plans · Coverage · Lab Tests (pathology) · NY · OB-GYN, Genetics, PathologyMedium impact

Non-Invasive Prenatal Testing 2.02.25

Effective date
Not stated in the notice
Identified
Jun 20, 2026

Summary

Excellus BlueCross BlueShield policy 2.02.25 finds non-invasive prenatal testing (NIPT) medically appropriate to screen for trisomy 21, 13 and 18 in singleton pregnancies, and finds NIPT for twin zygosity not medically necessary. The policy lists NIPT as investigational for multiple gestations, other aneuploidies, microdeletions, fetal sex chromosome aneuploidy, single-gene disorders, rolling circle replication screening, fetal nasal bone measurement and fetal RhD genotyping. A policy edit dated 05/13/26 removed Vasistera as an example for single-gene disorder testing and states that Vasistera is a limited NIPT for common chromosomal aneuploidies that is investigational.

Get alerts when payers change rules like this one

We check Excellus BlueCross BlueShield and other payers every day and email you when a change matches your specialty and state.

Get Excellus BlueCross BlueShield alertsPolicy Monitoring is free. No card required.

What to do

Action · 6 steps
01Check current applicability: the policy's stated next review date was April 2026.
02NIPT should only be offered in the context of informed consent, education and counseling by a qualified provider, such as a certified genetic counselor.
03Abnormal NIPT results should be confirmed with chorionic villi sampling (CVS) or amniocentesis.
04Patients with a positive screening result should have genetic counseling and comprehensive ultrasound, and should be offered diagnostic testing.
05The policy marks codes 81422, 81479, 81599, 0327U, 0449U, 0489U, 0494U and 0536U as (E/I) experimental/investigational, and code 0060U as (NMN) not medically necessary.
06Codes may not be covered under all circumstances, and services are contract dependent; if a product does not cover a service, the medical policy criteria do not apply.

Codes mentioned

768137681481420814228147981507815998416384704

Original notice

Non-Invasive Prenatal Testing 2.02.25
excellusbcbs.com · Always check the source before changing claims.
View original ↗

Related changes

See all Excellus BlueCross BlueShield changes →
Non-Invasive Prenatal Testing - (Effective Date - 2026-08-17) 2.02.25MediumEffective Aug 17, 2026 · Lab Tests (pathology)Non-Invasive Prenatal Testing - (Effective Date - 2026-08-17) 2.02.25MediumEffective Aug 17, 2026 · Lab Tests (pathology)Molecular Testing in the Management of Pulmonary Nodules 2.02.58MediumEffective Oct 22, 2026 · Lab Tests (pathology), Lungs (Respiratory)Gene Expression Profiling for Cutaneous Melanoma 2.02.52MediumEffective Oct 16, 2025 · Cancer Treatment (Oncology)Browse every Excellus BlueCross BlueShield change in the policy list

Related policy hubs

Excellus BlueCross BlueShield policiesNY policy changesOB-GYNGeneticsPathologyCode 76813Code 76814Code 81420Code 81422Code 81479Code 81507Code 81599Code 84163Code 84704

Summaries are AI-assisted. Always confirm against the original payer notice.

What is PolicyChanges

One workspace for payer rules, prior auth, coding and compliance

Medical practices use PolicyChanges to catch payer changes before they cause denials. Every change is summarized in plain English, with the codes involved, the date it takes effect and what to do.

Policy MonitoringPayer policy, prior auth and coding changes, filtered to your saved searchesOIG ScreeningStaff and vendors screened every month against OIG LEIE, SAM.gov and state Medicaid listsPrior Auth LookupKnow if a service needs prior authorization before you schedule itCredentialing TrackerLicenses, CAQH, Medicare revalidation and payer enrollments, with reminders before anything lapsesCompliance CenterKeep your HIPAA program documented and ready to show
Start freePolicy Monitoring is free. No card required.
Get alerts for changes like thisPolicy Monitoring is free. No card required.Create a free account