Calcitriol, Etelcalcetide, and Paricalcitol Injections (CPB 0022, reviewed 2026-02-11)
Aetna considers calcitriol, etelcalcetide (Parsabiv) and paricalcitol (Zemplar) injections medically necessary for commercial medical plans only for the listed indications in members with chronic kidney disease on hemodialysis. Each of these medications must be prescribed by or in consultation with an endocrinologist or a nephrologist. Etelcalcetide is medically necessary only for members with a contraindication, intolerance or ineffective trial of the equivalent alternatives, and continuation is medically necessary when the member shows benefit from therapy.