R14022OTN: International Classification of Diseases, 10th Revision (ICD-10) and Other Coding Revisions to National Coverage Determinations (NCDs)- April 2027.
CMS Transmittal 14022, dated October 23, 2026, is a quarterly maintenance update of ICD-10 coding and other coding updates for National Coverage Determinations, and it states that no policy is being changed as a result of these updates. The transmittal's stated effective date is April 1, 2027, with an implementation date of April 5, 2027, while the code changes in its table are dated September 30, 2026 (end dates) and October 1, 2026 (additions). The table also adds CPT 81459 for PGDX elio tissue complete CDx effective FDA approval July 30, 2026, until a specific PLA code is established, and adds HCPCS J9066 to the chemotherapy drugs associated with NCD 110.18 effective October 1, 2026.