Voretigene Neparvovec-rzyl (Luxturna) (CPB 0927, reviewed 2026-04-20)
Aetna covers voretigene neparvovec-rzyl (Luxturna) for commercial medical plans, and precertification is required of all Aetna participating providers and members in applicable plan designs. Aetna considers one-time administration per eye medically necessary for biallelic RPE65 mutation-associated retinal dystrophy when the member meets the listed criteria. Repeat administration in the same eye is considered experimental, investigational, or unproven, and the medication must be prescribed by or in consultation with an ophthalmologist.