MA08.151e, Monoclonal Antibodies Directed Against Amyloid for the Treatment of Alzheimer's Disease
Independence Blue Cross updated MA08.151e to clarify coverage for monoclonal antibodies directed against amyloid (aducanumab, lecanemab, donanemab) for Alzheimer's disease treatment. These drugs remain experimental/investigational and NOT covered except through Medicare's Coverage with Evidence Development (CED) program for patients enrolled in approved clinical studies. Billing teams must ensure claims for these medications are only submitted when patients are actively enrolled in CED clinical trials.