Blue Cross & Blue Shield of Mississippi · Identified Jun 20, 2026Medium impact
Tumor Treating Fields Therapy
Tumor treating fields therapy is considered medically necessary as an adjunct to standard maintenance therapy with temozolomide in individuals with newly diagnosed glioblastoma multiforme following initial treatment with surgery, radiotherapy, and/or chemotherapy, under these conditions: age 18 years or older, a supratentorial tumor, a Karnofsky Performance Status score of 70% or higher, and an individual who understands device use, including the requirement for a shaved head, and is willing to comply with use criteria according to the FDA label. Tumor treating fields therapy is considered investigational in all other conditions, including as an adjunct or alternative to standard medical therapy for progressive or recurrent glioblastoma multiforme, for brain metastases, for cancer in areas other than the brain, and as an adjunct to standard medical therapy for malignant pleural mesothelioma or non-small cell lung cancer (NSCLC).