Aetna · Identified Aug 19, 2026Medium impact
Infectious Diseases: Selected Tests (CPB 1008, reviewed 2026-01-14)
This Aetna policy addresses metagenomic next-generation sequencing, multiplex immunoassay tests, molecular syndromic panels and other tests for infectious diseases that do not fit in other bulletins. RT-QuIC is considered medically necessary for evaluating individuals with rapidly progressive dementia suspected of prion disease, and syphilis non-treponemal and treponemal tests are considered medically necessary for screening all pregnant women and persons at risk of syphilis, and for diagnostic testing of individuals with signs and symptoms of syphilis. Aetna considers named tests such as the Karius Test, IntelliSep, MeMed BV, TriVerity and the Synovasure Comprehensive PJI Test Panel experimental, investigational or unproven.