Question 1

What insurance policy changes affect CPT 88291?

Accepted Answer

There are 3 tracked policy changes affecting CPT 88291, including updates from Aetna, Blue Cross NC. Each change may modify coverage criteria, reimbursement rates, or prior-authorization requirements.

Question 2

Which payers have updated policy for CPT 88291?

Accepted Answer

Payers that have issued tracked updates for CPT 88291 include: Aetna, Blue Cross NC.

Question 3

How do I get notified when CPT 88291 policy changes?

Accepted Answer

Create a free account at PolicyChanges.app and save a search filtered to CPT 88291. You will receive a daily digest email whenever a new policy change references this code.

Question 4

Why do payers change policies for CPT 88291?

Accepted Answer

Payers revise policies for individual billing codes to align with updated clinical guidelines, CMS rule changes, fraud and abuse prevention measures, or network cost-management goals. Changes can affect medical necessity criteria, place-of-service restrictions, bundling rules, or whether a code requires prior authorization.

88291 Insurance Policy Changes

Prostate Cancer Screening (CPB 0521, reviewed 2025-11-25)

Invasive Prenatal Diagnosis of Genetic Diseases (CPB 0358, reviewed 2026-05-22)

Medical Policy Update for April 1, 2025