Multiplex Pathogen Identification Panels for Infectious Disease - Medicare Advantage (Revised)
Humana Medicare Advantage revised its policy on multiplex pathogen identification panels for infectious disease, effective 11/02/2026. The policy confirms coverage of molecular syndromic panels (including bloodstream, gastrointestinal, respiratory, meningoencephalitis, urinary tract, and other infection panels) when ordered by treating physicians and medical necessity criteria are met, following applicable CMS LCD/LCA guidance by MAC jurisdiction. Billing teams must verify that claims include the correct CPT or HCPCS codes for the specific panel type and confirm the member's MAC jurisdiction to apply the correct LCD/LCA requirements.