Barrett's Esophagus (CPB 0728, reviewed 2026-10-26)
Aetna's Clinical Policy Bulletin 0728 on Barrett's esophagus (reviewed 2026-10-26) considers radiofrequency ablation medically necessary for members with low-grade dysplasia confirmed by histology from 2 or more endoscopies 3 or more months apart. For members with high-grade dysplasia by biopsy, it considers endoscopic mucosal resection, esophagectomy, fundoplication, photodynamic therapy and radiofrequency ablation medically necessary, and it considers argon plasma coagulation, cryotherapy, laser therapy and several other listed interventions and tests experimental, investigational, or unproven because their effectiveness has not been established.