Medium impact
HIV Testing (CPB 0542, reviewed 2025-11-26)
Aetna·Effective Nov 26, 2025
Aetna has updated its HIV Testing Medical Clinical Policy Bulletin (CPB 0542) effective 2025-11-26, establishing coverage criteria for HIV screening and diagnostic testing using FDA-approved algorithms including antigen/antibody combination immunoassays, HIV-1/HIV-2 differentiation tests, and nucleic acid tests (NAT). The policy explicitly excludes coverage for home HIV test kits that do not require a physician's prescription. Billing teams must ensure claims are submitted only for physician-prescribed tests using the specified covered codes and testing algorithms.