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[California] Lenalidomide is now available with end‑to‑end REMS support

Anthem BCBS·CA · Oncology, Hematology·Provider Bulletin
Effective date
May 1, 2026
We identified it
May 3, 2026
Days to comply

Summary

Anthem Blue Cross (California) now offers lenalidomide through BioPlus Specialty Pharmacy with end-to-end REMS (Risk Evaluation and Mitigation Strategies) management. This streamlines prior authorization and therapy initiation for oncology/hematology practices, with BioPlus handling the full REMS process to reduce administrative burden and accelerate patient access to treatment.

Action Required

Action needed
Effective May 1, 2026: Oncology and hematology providers prescribing lenalidomide to Anthem Blue Cross California members should route all new prescriptions and REMS management through BioPlus Specialty Pharmacy (NCPDP 1078535, Fax: 800-269-5493, bioplusrx.com) instead of previous channels. Billing and clinical staff should update internal referral lists and provider workflows to direct lenalidomide cases to BioPlus. Communicate this change to prescribers and front-desk staff to ensure proper routing. Use Availity Chat with Payer (https://Availity.com) during business hours for eligibility, authorization, and claims status questions. Failure to route through BioPlus may delay REMS approval and therapy initiation.