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CommercialPrior AuthHigh impact

Genetic Testing Update

Blue Cross Blue Shield of Nebraska·NE · Oncology, Hematology, OB-GYN +6 more·Medical Policy
Effective date
Jan 1, 2025
We identified it
Jun 19, 2026
Days to comply

Summary

Blue Cross Blue Shield of Nebraska is updating genetic testing policies effective January 1, 2025, requiring preauthorization for hereditary cancer susceptibility panels, tumor analysis, and circulating tumor DNA testing. Multiple new coverage criteria and billing codes are being added for specific genetic tests including BRCA panels, neuroendocrine cancer panels, and liquid biopsy testing.

Action Required

Action needed
Before January 1, 2025: Billing team must update system to require preauthorization for all genetic testing codes listed in the policy (hereditary cancer panels, tumor analysis, HLA typing, and circulating tumor DNA tests). Update encounter forms and EMR templates to remind providers of new prior auth requirements. Train staff on new medical necessity criteria for each test type. Failure to obtain preauthorization will result in claim denials.

Affected Billing Codes

81162
81163
81164
81165
81166
81167
81216
81307
81321
81351
81432
81433
81437
81438
81479
81405
81406
81404
81370
81371
81372
81373
81376
81378
81379
81380
81382
81241
81240