Medicare AdvantageBilling CodesMedium impact
MA08.026l, Treatments for Complex Regional Pain Syndrome (CRPS)
Independence Blue Cross·Pain Management, Anesthesiology, Neurology +2 more·Medical Policy
Effective date
Oct 1, 2025
We identified it
Jun 19, 2026
Summary
Independence Blue Cross Medicare Advantage policy MA08.026o (effective 10/01/2025) updates HCPCS coding for mannitol injections used in Complex Regional Pain Syndrome treatment. Code J2150 (mannitol 25% in 50 ml) has been deleted and replaced with J2151 (mannitol 250 mg), requiring billing system updates to reflect the new dosage-based coding structure.
Action Required
By October 1, 2025: Billing team must update all billing software and systems to discontinue use of HCPCS code J2150 (Injection, mannitol, 25% in 50 ml) and replace with new code J2151 (Injection, mannitol, 250 mg) for Complex Regional Pain Syndrome treatments. Verify that all claims submitted after 10/01/2025 using J2150 will be denied; train billing staff on the new dosage-based code structure. Update encounter templates and fee schedules in the billing system. Communicate the change to providers performing sympathetic nerve blocks and epidural infusions to ensure they document mannitol administration with the correct new code on clinical notes.