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Medicare AdvantageCoverageMedium impact

MA08.114i, Fam-trastuzumab deruxtecan-nxki (Enhertu®)

Independence Blue Cross·Oncology, Hematology·Pharmacy
Effective date
Apr 6, 2026
We identified it
Jun 19, 2026
Days to comply

Summary

Medicare Advantage updated medical necessity criteria and medical coding requirements for fam-trastuzumab deruxtecan-nxki (Enhertu®), a specialty oncology drug. This affects billing and coverage determination for this targeted cancer therapy.

Action Required

Action needed
Before April 6, 2026: Oncology billing team must review updated medical necessity criteria for Enhertu® (fam-trastuzumab deruxtecan-nxki) in Medicare Advantage plans. Update prior authorization workflows and ensure documentation meets new medical necessity requirements. Verify correct coding procedures for this specialty oncology drug to prevent claim denials.