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CommercialBilling CodesMedium impact

11.03.17a, Peroral Endoscopic Myotomy (POEM) Procedures

Independence Blue Cross·PA · Gastroenterology, General Surgery·Medical Policy
Effective date
Jan 5, 2026
We identified it
Jun 19, 2026
Days to comply
—

Summary

Independence Blue Cross updated policy 11.03.17a to replace CPT code 43999 with CPT code 43499 for diverticular peroral endoscopic myotomy (D-POEM) and zenker peroral endoscopic myotomy (Z-POEM) procedures. Both procedures remain classified as experimental/investigational and not covered. The medically necessary coverage criteria for standard POEM (achalasia type III with Eckardt score >6) remain unchanged.

Action Required

Action needed
By January 5, 2026: Billing team must update billing system and encounter forms to replace CPT code 43999 with CPT code 43499 for D-POEM and Z-POEM procedures. Remove all references to 43999 from billing templates and system rules. Ensure claims for D-POEM and Z-POEM continue to be denied as experimental/investigational. Verify that CPT 43497 (standard POEM for achalasia type III) is set to require medical necessity documentation including esophageal manometry results and Eckardt score >6 before processing. Claims submitted with incorrect codes or without proper achalasia documentation will be denied.

Affected Billing Codes

43497
43499
43999
K22.0