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06.02.01m, Lyme Disease: Diagnosis and Intravenous (IV) Antibiotic Therapy

Independence Blue Cross·Infectious Disease, Internal Medicine, Neurology +3 more·Medical Policy
Effective date
Apr 1, 2026
We identified it
Jun 19, 2026
Days to comply
—

Summary

Independence Blue Cross updated policy 06.02.01m effective 04/01/2026 to revise the CPT code narrative for 0580U as part of an annual CPT code update. The policy itself—covering Lyme disease diagnosis methods (ELISA, Western blot, PCR) and IV antibiotic therapy criteria—remains substantively unchanged; this is a technical code documentation update with no new billing requirements.

Action Required

Action needed
No immediate action required. This is a coding update memo that revises CPT code narrative documentation for 0580U only; the policy bulletin itself was not fully re-reviewed. Billing team should verify that current billing software and claim submission processes already support the listed CPT codes (86617, 86618, 87475, 87476), HCPCS codes (S9494, S9497), and ICD-10 diagnosis codes (A69.20-A69.29) for Lyme disease testing and IV antibiotic therapy. If 0580U is used in your practice, confirm the updated narrative in your reference materials by 04/01/2026. No workflow changes or prior authorization modifications are indicated by this update.

Affected Billing Codes

86617
86618
87475
87476
S9494
S9497
A69.20
A69.21
A69.22
A69.23
A69.29