Billing team should review and implement the following source-backed coverage criteria: (1) Verify that laser trabeculoplasty (CPT 65855) is documented as first-line treatment for primary open-angle glaucoma before submitting claims; (2) For aqueous drainage implant codes (0449T, 0450T, 66180, 66183, 66185, 66989, 66991), confirm prior failure of first-line medications (latanoprost, timolol) and second-line medications (brimonidine, dorzolamide) for refractory cases; (3) For micro-bypass stent codes (iStent, Hydrus), verify concurrent cataract surgery, mild-to-moderate glaucoma diagnosis, and current ocular hypotensive therapy; (4) For trabecular meshwork cutting devices used in goniotomy/ab interno trabeculotomy, ensure procedure is medically necessary per listed indications (pediatric/congenital glaucoma, JOAG, failed medical therapy, or inability to comply with therapy) and do NOT bill with other angle surgeries; (5) Deny or request clinical documentation for codes listed as experimental/investigational (0253T, 0444T, 0445T, 0474T, 0671T, iStent G3 Supra, iStent Infinite, FLIGHT, MINT, beta radiation) as they are not covered; (6) Confirm XEN Glaucoma Treatment System (CPT code not separately listed but referenced) is used only for refractory glaucoma unresponsive to maximum tolerated medical therapy, and do NOT cover XEN gel stent replacement; (7) Deny mitomycin C (J7315) or systemic corticosteroids (J9190) with aqueous shunt implants except when used adjunctively with Ex-PRESS mini glaucoma shunt only. Update billing system edits, prior authorization forms, and claim denial protocols to enforce these criteria. Verify current applicability with Aetna before processing claims, as this represents the 2026-10-14 reviewed policy.