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Hematopoietic Cell Transplantation for Chronic Myelogenous Leukemia (CPB 0674, reviewed 2026-10-07)

Aetna·Hematology, Oncology, Transplant Surgery·Medical Policy
Effective date
Not stated
We identified it
Oct 12, 2026
Days to comply
—

Summary

This is a policy review (not a change) of Aetna's Clinical Policy Bulletin 0674 on hematopoietic cell transplantation for chronic myelogenous leukemia, last reviewed on 2026-10-07. The policy maintains coverage for allogeneic HCT when patients fail tyrosine kinase inhibitors and classifies autologous HCT as experimental/investigational. No effective date for coverage changes is stated in the source.

Action Required

Action needed
Verify current applicability of this policy with Aetna. The billing team should confirm: (1) whether the practice submits claims for allogeneic HCT (CPT 38205, 38230, 38240, 38242; HCPCS S2150) for CML patients who have failed tyrosine kinase inhibitors (imatinib, dasatinib, nilotinib, bosutinib, ponatinib, asciminib) without serious organ dysfunction; (2) ensure prior authorization is obtained from the transplanting institution's written eligibility criteria; (3) reject or deny claims for autologous HCT (CPT 38206, 38232, 38241) for CML as this remains classified as experimental/investigational under Aetna coverage; (4) confirm ICD-10 codes C92.10 and C92.11 are correctly linked to covered transplant procedures. This is a policy review, not a new implementation deadline.

Affected Billing Codes

38205
38230
38240
38242
38206
38232
38241
S2150
S0088
C92.10
C92.11