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CommercialPrior AuthMedium impact

Pancreas Transplantation Alone (PTA) and Islet Cell Transplantation (CPB 0601, reviewed 2026-09-18)

Aetna·Transplant Surgery, Endocrinology, Internal Medicine·Medical Policy
Effective date
Not stated
We identified it
Sep 30, 2026
Days to comply
—

Summary

Aetna updated its clinical policy for Pancreas Transplantation Alone (PTA) and Islet Cell Transplantation (CPB 0601), reviewed 2026-09-18. This policy establishes medical necessity criteria, precertification requirements for Lantidra suspension, covered CPT codes (0584T, 0585T, 0586T, 48160, 48550-48552, 48554, 48556), and defines absolute/relative contraindications. Billing teams must implement precertification workflows and ensure compliance with the detailed selection criteria for coverage.

Action Required

Action needed
By 2026-09-18, billing and prior authorization teams must: (1) Update authorization workflows to require MANDATORY precertification for donislecel-jujn (Lantidra) suspension through National Medical Excellence (NME) at 877-212-8811 for all Aetna participating providers and members in applicable plan designs; (2) Configure billing system to flag CPT codes 0584T, 0585T, 0586T, 48160, 48550-48552, 48554, and 48556 for prior auth review; (3) Create checklist documenting verification of all medical necessity criteria (general criteria, disease-specific criteria, and absence of absolute contraindications) before claim submission; (4) Train providers on relative contraindication exceptions requiring supporting documentation within 4 weeks demonstrating 3 months stability for substance abuse/psychiatric issues; (5) Implement tracking to ensure Lantidra infusions do not exceed maximum of 3 infusions per member. Failure to obtain precertification will result in claim denials.

Affected Billing Codes

48160
48550
48551
48552
48554
48556
36481