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Medicare AdvantagePrior AuthHigh impact

Medicare Part B Step Therapy Oct Updates

Florida Blue·FL · Oncology, Rheumatology, Hematology +3 more·Medicare
Effective date
Oct 1, 2026
We identified it
Sep 25, 2026
Days to comply
—

Summary

Florida Blue Medicare has updated its Part B Step Therapy program effective October 1, 2026, restructuring preferred and non-preferred medication classifications across six drug categories (Autoimmune Therapy, Bone Remodeling Agents, Cancer and Supportive Therapy, Colony-Stimulating Factors, Complement Inhibitors, and Ophthalmic Agents). Billing teams must verify that prescriptions align with updated preferred product lists and implement prior authorization requirements for non-preferred medications to prevent claim denials.

Action Required

Action needed
By September 30, 2026: Billing team must update the claims processing system to enforce the revised Part B Step Therapy preferred/non-preferred product classifications across all six drug categories (Autoimmune Therapy, Bone Remodeling Agents, Cancer and Supportive Therapy, Colony-Stimulating Factors, Complement Inhibitors, and Ophthalmic Agents). Configure the system to automatically flag and require prior authorization for all non-preferred HCPCS codes listed in the policy before processing claims. Providers must be notified of preferred product alternatives to facilitate prescribing decisions. Update denial management protocols to reflect the new classifications. Failure to implement these changes will result in claim rejections and denials for non-compliant prescriptions effective October 1, 2026.

Affected Billing Codes

J3262
Q5135
Q5156
Q5133
Q9997
Q5099
Q9998
J3358
Q9999
J3489
Q5167
Q5157
Q5162
J0897
J3111
Q5158
Q5159
Q5161
Q5136
Q5166
C9399
J3590
J0640
J0643
J0641
J0642
J3490
C9310
J0644
Q5107
Q5118
J9035
Q5126
Q5129
Q5160
J9171
J9232
J9172
J9174
Q5165
Q5171
J1447
Q5101
Q5110
J1442
Q5125
J2820
Q5172
J1303
J9332
J9334
J9333
Q5151
J1823
J1300
J1299
J1307
Q5152
J9256
C9257
Q5124
Q5128
J0178
J0177
J2778
J2777
J3396
Q5147
Q5149
Q5150
Q5153
Q5155
Q5170
Q5168
J0179
J2779