Back to dashboard
Medicare AdvantageBilling CodesHigh impact

Update for CPT Codes 80320-80377: Effective 10/1/2026

Ambetter·IN·Coding
Effective date
Oct 1, 2026
We identified it
Aug 26, 2026
Days to comply
16 days

Summary

Effective October 1, 2026, CPT codes 80320-80377 (Definitive Drug Testing Procedures) will no longer be reimbursable by Ambetter Health. Billing teams must transition to G-series bundled laboratory codes for all drug testing claims to avoid denials.

Action Required

Before Oct 1, 2026
By September 30, 2026: Billing team must update billing software to block all claims using CPT codes 80320-80377 for Ambetter Health plans and replace them with appropriate G-series bundled laboratory codes. Create a crosswalk mapping document identifying which G-series code corresponds to each CPT code being discontinued. Review all standing orders and encounter templates in the EMR to remove references to CPT 80320-80377. Communicate the change to all providers and laboratory staff to ensure compliance. Beginning October 1, 2026, any claims submitted with CPT codes 80320-80377 to Ambetter Health will be denied. Contact your Ambetter Provider Relations Representative if you need guidance on specific G-series code substitutions.

Affected Billing Codes

80320
80321
80322
80323
80324
80325
80326
80327
80328
80329
80330
80331
80332
80333
80334
80335
80336
80337
80338
80339
80340
80341
80342
80343
80344
80345
80346
80347
80348
80349
80350
80351
80352
80353
80354
80355
80356
80357
80358
80359
80360
80361
80362
80363
80364
80365
80366
80367
80368
80369
80370
80371
80372
80373
80374
80375
80376
80377