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Ambetter Health Billing Code Update for CPT Codes 80320-80377 Effective 10/01/2026

Ambetter·Pathology, Occupational Medicine, Pain Management +2 more·Coding
Effective date
Oct 1, 2026
We identified it
Aug 26, 2026
Days to comply
16 days

Summary

Ambetter Health will no longer reimburse CPT codes 80320-80377 (Definitive Drug Testing Procedures) effective October 1, 2026. Providers must transition to G-series bundled laboratory codes for all drug testing claims submitted to Ambetter plans after this date.

Action Required

Before Oct 1, 2026
By September 1, 2026: Billing team must update billing software and claims submission rules to block submission of CPT codes 80320-80377 to Ambetter Health plans. Create mapping documentation identifying the appropriate G-series bundled laboratory codes as replacements for each discontinued CPT code. Communicate the transition plan to laboratory staff and providers who perform or order definitive drug testing. After October 1, 2026, any claims submitted with CPT codes 80320-80377 to Ambetter will be denied. Verify all Ambetter claims with drug testing procedures are recoded to the corresponding G-series bundled codes before submission.

Affected Billing Codes

80320
80321
80322
80323
80324
80325
80326
80327
80328
80329
80330
80331
80332
80333
80334
80335
80336
80337
80338
80339
80340
80341
80342
80343
80344
80345
80346
80347
80348
80349
80350
80351
80352
80353
80354
80355
80356
80357
80358
80359
80360
80361
80362
80363
80364
80365
80366
80367
80368
80369
80370
80371
80372
80373
80374
80375
80376
80377