CommercialCoverageLow impact
Ultra Rapid Detoxification (UROD) (CPB 0317, reviewed 2026-05-21)
Aetna·Psychiatry, Anesthesiology, Internal Medicine·Medical Policy
Effective date
May 21, 2026
We identified it
Aug 18, 2026
Summary
Aetna has classified Ultra Rapid Detoxification (UROD) as experimental, investigational, or unproven and will not cover this procedure for opioid use disorder treatment or any other indication. There is no specific CPT code for UROD itself, but related naloxone injection codes (J2312, J2313) and opioid-related ICD-10 codes are identified as non-covered when billed for UROD indications. This is a coverage denial policy effective immediately.
Action Required
Effective immediately (as of May 21, 2026): Billing and prior authorization teams must deny all claims for Ultra Rapid Detoxification (UROD) procedures as experimental/unproven under Aetna plans. If claims for UROD are submitted with CPT codes related to anesthesia, procedures, or facility services in combination with naloxone codes (J2312, J2313) and opioid-related ICD-10 codes (F11.10-F11.29, T40.0X1-T40.695), flag and deny as non-covered. Update internal billing guidelines and prior authorization protocols to reflect UROD non-coverage. Train billing staff to recognize UROD-related claim submissions and apply the non-coverage determination. Notify providers in-network that Aetna will not authorize or pay for UROD procedures. No prior authorization will be granted for this procedure. Claims submitted after this date without recognition of the non-coverage policy may delay denials.