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Influenza Rapid Diagnostic Tests (CPB 0476, reviewed 2026-07-24)

Aetna·Emergency Medicine, Family Medicine, General Practice +3 more·Medical Policy
Effective date
Jul 24, 2026
We identified it
Aug 18, 2026
Days to comply

Summary

Aetna has updated its medical policy on influenza rapid diagnostic tests (CPB 0476), clarifying coverage for multiple testing modalities including rapid molecular assays, multiplex assays detecting flu/COVID/RSV, and antigen-based tests. The policy emphasizes that confirmatory molecular testing is medically necessary following negative rapid antigen tests (RIDTs) during high community influenza activity due to their moderate 50-70% sensitivity. Billing teams must ensure claims for these tests include appropriate medical necessity documentation and use correct CPT codes based on test type.

Action Required

Action needed
REQUIREMENTS: By August 7, 2026 (urgent - policy is 1 day old and already effective): - Billing team must update claim submission protocols to ensure influenza rapid test claims (CPT 87275, 87276, 87400, 87501, 87502, 87804, and multiplex codes 87634-87637) include medical necessity documentation confirming that results will inform clinical management, antiviral treatment decisions, or infection control measures. - Provider education staff must notify all clinicians that negative RIDT results (CPT 87275, 87276, 87400, 87804) NOW REQUIRE confirmatory molecular testing (CPT 87501, 87502) during high community influenza activity periods. Update EMR templates and encounter forms to reflect this requirement. - Billing software must be configured to flag claims for negative RIDT tests without corresponding molecular confirmatory test orders during flu season for manual review to prevent claim denials. - Front desk and laboratory staff must ensure specimen type and test type documentation is captured on orders, as different tests require different specimen types (throat, nasopharyngeal, or nasal). - Billing team must cross-reference appropriate ICD-10 codes (B34.9, J10.00-J11.89, R05.1-R05.9, R50.9, R06.02, R51.0-R51.9, R53.81) with test claims; claims without these or similar fever/respiratory symptom codes may be denied for lack of medical necessity. Failure to implement these changes will result in claim denials for influenza testing without proper medical necessity documentation and denial of confirmatory molecular tests when RIDTs are negative during high-activity periods.

Affected Billing Codes

87275
87276
87400
87501
87502
87634
87635
87636
87637
87804
B34.9
J10.00
J11.89
M79.10
M79.18
R05.1
R05.9
R50.9
R06.02
R51.0
R51.9
R53.81