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Hepatitis Screening (CPB 0835, reviewed 2025-12-09)

Aetna·Infectious Disease, Internal Medicine, Family Medicine +4 more·Medical Policy
Effective date
Dec 9, 2025
We identified it
Aug 17, 2026
Days to comply

Summary

Aetna updated its Hepatitis Screening policy (CPB 0835) effective 2025-12-09, establishing specific medical necessity criteria for HBV, HCV, and HDV screening across defined risk populations. The policy now covers one-time HCV screening for all adults aged 18+, while HEV screening remains experimental/investigational. Billing teams must verify patient eligibility against the detailed criteria before submitting claims using the specified CPT, HCPCS, and ICD-10 codes.

Action Required

Action needed
By 2025-12-09, the billing team must: (1) Update billing system rules to require verification that patients meet Aetna's medical necessity criteria for hepatitis screening before claim submission; (2) For HBV screening (CPT 86704, 86705, 86706, 87340, 87341, HCPCS G0499), verify patient belongs to one of the specified high-risk categories (hemodialysis, healthcare workers with exposure, HIV+, injection drug users, pregnant women, etc.); (3) For HCV screening (CPT 86803, 86804, HCPCS G0472), note that one-time screening is now medically necessary for ALL adults 18+, not just high-risk groups; (4) For HDV screening (CPT 86692), confirm patient is HBsAg-positive AND meets ALL four risk factors: IV drug user status, HBV-DNA <2,000 IU/ml, ALT >40 U/L, and HDV endemic country origin; (5) Add documentation requirement fields to encounter forms requiring providers to document which specific criteria are met; (6) Do NOT bill CPT codes for HEV (hepatitis E) screening, as it remains experimental/investigational; (7) Map appropriate ICD-10 codes from the policy's coverage list to each claim. Claims submitted without documented medical necessity meeting these criteria will be denied by Aetna.

Affected Billing Codes

86704
86705
86706
87340
87341
G0499
86803
86804
G0472
86692