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Intermittent Intravenous Insulin Therapy (CPB 0742, reviewed 2025-11-26)

Aetna·Endocrinology, Internal Medicine, Family Medicine +1 more·Medical Policy
Effective date
Nov 26, 2025
We identified it
Aug 16, 2026
Days to comply

Summary

Aetna's updated policy (CPB 0742, effective 2025-11-26) classifies intermittent intravenous insulin therapy and related diagnostic testing as experimental and investigational, making these services non-covered. Billing teams must deny claims for pulsatile intravenous insulin therapy, hepatic activation therapy, and associated glucose/potassium monitoring tests when billed under the listed CPT/HCPCS codes. Exception: standard insulin infusions for diabetic ketoacidosis or hyperosmolar coma remain covered.

Action Required

Action needed
By 2025-11-26: Billing team must update claim denial rules to reject all claims for intermittent/pulsatile intravenous insulin therapy (PIVIT, hepatic activation therapy, metabolic activation therapy, Trina Health artificial pancreas) and associated diagnostic testing. Specifically: (1) Flag and deny claims for HCPCS code G9147 (Outpatient Intravenous Insulin Treatment) with denial reason 'Non-covered experimental service per Aetna CPB 0742'; (2) Deny claims for CPT codes 82947, 82948, 82950, 84132, 84133, 84540 when billed in the context of intermittent IV insulin therapy with explanation that diagnostic testing in this context is experimental; (3) Deny claims for insulin J-codes (J1811-J1815, J1817) when associated with pulsatile/intermittent IV administration; (4) Deny all S5550-S5571 insulin supply codes when linked to PIVIT. Providers must be notified that these services are non-covered; claims will be denied automatically. Exceptions: Continue processing standard insulin infusions (CPT 96372, 90835 or applicable infusion codes) for diabetic ketoacidosis (DKA) and hyperosmolar coma - these remain covered. Update billing system to identify these procedure codes on encounter forms and flag for verification before claim submission.

Affected Billing Codes

82947
82948
82950
84132
84133
84540
G9147
J1811
J1812
J1813
J1814
J1815
J1817
S5550
S5551
S5552
S5553
S5554
S5555
S5556
S5557
S5558
S5559
S5560
S5561
S5562
S5563
S5564
S5565
S5566
S5567
S5568
S5569
S5570
S5571