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Upcoming Policies effective October 5, 2026

Blue Cross and Blue Shield of Minnesota·Ophthalmology, Wound Care, Orthopedics +1 more·Medical Policy
Effective date
Oct 5, 2026
We identified it
Aug 3, 2026
Days to comply
63 days

Summary

This policy revision updates coverage criteria for human amniotic membrane grafts and tumor treating fields (TTF) therapy, effective October 5, 2026. For amniotic membrane, only specific ophthalmic conditions and diabetic lower-extremity ulcers meeting strict criteria are medically necessary; all other uses are experimental. TTF therapy for newly diagnosed glioma now requires prior approval with specific clinical criteria including KPS score ≥60% and device compliance documentation.

Action Required

Before Oct 5, 2026
By October 5, 2026: Billing team must implement prior authorization requirements for amniotic membrane graft claims based on indication and product type. For ophthalmic uses, verify diagnosis matches covered list (bullous keratopathy, corneal perforation, corneal ulcers, persistent epithelial defects, chemical burn, neurotrophic keratitis, Stevens-Johnson syndrome, limbal stem cell deficiency, pterygium, severe dry eye). For non-ophthalmic diabetic lower-extremity ulcers, require documentation that wound area decreased <20% after 2 weeks standard care. All other amniotic membrane applications must be denied as experimental. For TTF therapy claims, require prior authorization with documentation of: (1) newly diagnosed diffuse glioma (astrocytoma WHO grade 4 IDH-mutant OR supratentorial glioblastoma), (2) prior debulking surgery, (3) concurrent temozolomide use, (4) KPS score ≥60%, and (5) daily device wear ≥18 hours. Update billing system denial rules to automatically reject experimental/investigative amniotic membrane products listed in Section III and IV unless prior authorization is obtained. Communicate policy changes to providers in ophthalmology, wound care, orthopedics, and oncology to ensure proper documentation at point of care. Claims submitted after October 5, 2026 without proper authorization or meeting medical necessity criteria will be denied.